clinicaltrials相关论文
Advances in the treatment of gastroenteropancreatic neuroendocrine neoplasms with somatostatin analo
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目的:探讨降糖药物临床试验中糖尿病受试者的管理要点和伦理考虑。方法:以运城市中心医院降糖药物临床试验中受试者管理为例，系统阐......
目的:根据国家药品监督管理局新颁布的GCP法规，探讨临床试验期间可疑且非预期严重不良反应报告的管理模式。方法:通过GCP法规结合实......
结直肠癌是全球第三大肿瘤，治疗手段包括手术、化疗、放疗和靶向治疗等。免疫检查点抑制剂的出现改写了许多瘤种的诊治指南。免疫检......
The neurotrophic signaling of glial cell line-derived neurotrophic factor (GDNF) with its canonical receptor, the recept......
Progress in clinical trials of cell transplantation for the treatment of spinal cord injury: how man
Spinal cord injury can lead to severe motor, sensory and autonomic nervous dysfunctions. However, there is currently no ......
Current Tracking on Effectiveness and Mechanisms of Acupuncture Therapy: A Literature Review of High
The scientific evidence of acupuncture studies has been improved in recent years,and one of the important manifestations......
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Owing to its unique superiority in improving quality of life and prolonging survival time among advanced lung cancer pat......
Two randomized controlled trials of acupuncture concerning polycystic ovary syndrome (PCOS) and stress urinary incontine......
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Parkinson\'s disease (PD) is a complex neurodegenerative disorder with no cure in sight.Clinical challenges of the dis......
Objectives: To investigate cancer patients acceptance of clinical trials, and explore properly related factors in order ......
Over the last decades,the development of novel cancer therapeutics is often plagued by discrepancies between drug effica......
Clinical and translational studies of HDAC inhibitors in cutaneous T-cell lymphomas-美国得州大学MD安得森癌症中心之
Epigenetic modification with small molecule histone deacetylase inhibitors (HDACi) has been a promising new anti-neoplas......
Effect of food and gender on single-dose pharmacokinetics of Ginsenoside C-K tablets in healthy Chin
Objective: Ginsenosides C-K has a potentiality to develope to a new drug for rheumatoid arthritis,this was a first-in-hu......
Aim: The anti-diabetic drug metformin exerts chemopreventive and antineoplastic effects in many types of malignancies.We......
Atrial fibrillation(AF)is associated with significant morbidity and mortality,and increases the risk of stroke by 5-fold......
In oncology clinical development,randomized phase Ⅱ studies have been increasingly used in recent years for a variety o......
Functional data analysis is powerful in analyzing data that can be represented by curves or images....
Nowadays,Adaptive Bayesian Sequential Design(ABSD)has been increasingly applied in various phase Ⅰ and Ⅱ clinical tria......
An Adaptive Bayesian Sequential Design for Determining the Subject-Specific Optimal Treatment Length
While Bayesian adaptive designs have been widely used to find the optimal dose to be used in patients,and to select the ......
The Achilles’ Heel of Pancreatic Cancer: Targeting pancreatic cancer’s unique immunologic characteri
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Design and analysis of high-risk medical device clinical trials for diabetes monitoring and treatmen
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目的建立冠心病与抗栓临床研究创新网络平台（CardiaCare）的标准化数据字段定义，以期促进国内外数据平台的互认互通，增强平台对多中心临......
Methods for development of a core outcome set for clinical trials integrating traditional Chinese me
Clinical trial outcome reporting differs between studies integrating traditional Chinese medicine (TCM)and Western medic......
目的了解国内药物临床试验相关伦理审查研究的发展动态，为今后的研究提供参考依据。方法通过检索中国知网和万方全文数据库，回顾2003......
随着我国创新药品器械研发能力的不断提高,开展医疗器械临床试验的项目数量也在不断增多。医疗器械临床试验是验证器械安全性的重......
目的在扩大临床应用基础上，考察国产^99Tc^m-双半胱氨酸（Ec）注射液的有效性、安全性和不良反应。方法全国8个省、市的14家医院参加了......
In clinical research,our aim is to design a study which would be able to derive a valid and meaningful scientific conclu......
The effect of early goal-directed therapy on outcome in adult severe sepsis and septic shock patient
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Omalizumab for the treatment of chronic spontaneous urticaria: a meta-analysis of randomized clinica
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IntroductionrnSeveral research designs usually underpin economicevaluations in healthcare regulatory systems. Theseinclu......
Liposomes are artificial, spherical, closed vesicles consisting of one or more lipid bilayer (s). Liposomes made from es......
期刊
研究证实,血浆维生素C浓度随给药途径的不同有着显著的差别.只有通过静脉注射给药,血浆和尿液当中的维生素C浓度才能达到杀死癌细......
目的：观察连参通淋片治疗非淋菌性尿道炎(湿热下注证)的临床疗效和安全性。方法用随机、双盲双模拟、平行对照的多中心研究,入选435......
Developing the criteria for evaluating quality of individualization in homeopathic clinical trial re
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Lesson Thirty-Four AHA/ACCF/HRS Recommendations for the Standardization and Interpretation of the El
With the advent of automated recording systems and the performance of large-scale, multicenter clinical trials, a large ......
第一章总则n 第一条为了使我国生物医学领域人类成体干细胞研究切实遵守我国的相关法规，使干细胞技术更好地为治疗人类疾病、增......
2017年美国食品药品管理局药品审评和研究中心再次更新了《药品生产企业临床药物相互作用研究：试验设计、数据分析、临床应用指南(......
Gastrointestinal cancers rank the leading position in common malignancies in China.How to combat the delay in diagnosis,......
数据监测委员会是由研究赞助者指定的一组临床医生和生物统计学家，对临床试验的安全性、科学有效性和完整性进行独立评估。在美国，食......
Biliary tract cancers (BTCs) comprise a group of hetero-geneous poor prognosis cancers with increasing incidence recent ......
